Iceman may hold earliest evidence of Lyme disease

New genetic analysis has revealed that the 5,300-year-old ice mummy dubbed Ötzi, discovered in the Eastern Alps about 20 years ago, appears to have had the oldest known case of Lyme disease, msnbc reported Tuesday.

As part of work on the Iceman’s genome ― his complete genetic blueprint ― scientists found genetic material from the bacterium responsible for the disease, which is spread by ticks and causes a rash and flu-like symptoms and can lead to joint, heart and nervous system problems, the report said.

The new analysis also indicates the Iceman was lactose intolerant, predisposed to cardiovascular disease, and most likely had brown eyes and blood type O, msnbc said.

To sequence the Iceman’s genome, researchers took a sample from his hip bone. In it, they looked for not only human DNA ― the chemical code that makes up genes ― but also for that of other organisms, the report said.

While they found evidence of other microbes, the Lyme disease bacterium, called Borrelia burgdorferi, was the only one known to cause disease, said Albert Zink, a study researcher and head of the European Institute for Mummies and the Iceman at the European Academy of Bozen/Bolzano (EURAC) in Italy, according to msnbc.

“Our data point to the earliest documented case of a B. burg­dorferi infection in mankind. To our knowledge, no other case report about borreliosis (Lyme disease) is available for ancient or historic specimens,” Zink and colleagues write in an article published on Feb. 28 in the journal Nature Communications. <Korea Times>

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